BDBM339822 US9757364, Compound 15

SMILES COc1cc(OC)cc(c1)N(CCO)c1ccc2ncc(-c3cnn(C)c3)c(Cl)c2n1

InChI Key InChIKey=MRSOJHDLCLHTOL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 339822   

TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Astex Therapeutics

US Patent
LigandPNGBDBM339822(US9757364, Compound 15)
Affinity DataIC50:  2.45nMAssay Description:In a final reaction volume of 30 μL, FGFR4 (h) (60 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent